Wolf-Dietrich Hardt

Golden Owl

Prof. Dr. Wolf-Dietrich Hardt


Deputy head of Institute of Microbiology


Full Professor

Contact Data

Tel.: +41 44 632 51 43
Fax: +41 44 632 11 29
Tel. (Sec.): +41 44 632 33 19

ORCID: 0000-0002-9892-6420


ETH Zürich
Wolf-Dietrich Hardt
Institut für Mikrobiologie
HCI  G 417
Vladimir-Prelog-Weg 1-5/10
8093 Zürich

Organisations Full Professor at the Department of Biology
Curriculum Vitae (CV)

Wolf-Dietrich Hardt was elected in October 2001 as a Professor for Microbiology at the Institute of Microbiology (D-BIOL) ETH Zurich. His group investigates the molecular mechanisms of infectious disease.


Wolf-Dietrich Hardt was born 3.6.1968 in Hannover (Germany). He grew up in Neustadt a. Rbge., a small village in the outskirts of Hannover. He is married and has 3 children. From 1987-92 Wolf-Dietrich Hardt studied biochemistry at the Freie Universität Berlin. He did his diploma- and PhD-theses (1992-1995) with Dr. Roland K. Hartmann in the group of Prof. Volker A. Erdmann at the institute of biochemistry, FU Berlin. There, he investigated the molecular function of catalytic RNAs. From 1995 to 1997 Wolf-Dietrich Hardt joined the group of Prof. Jorge E. Galan at Stony Brook, New York. During this inspiring time he began his work on the molecular mechanisms of Salmonella infections. Afterwards he moved to the Max von Pettenkofer Institute (group of Prof. Jürgen Heesemann) at the Ludwig Maximilians University in Munich. There, he continued his work on Salmonella pathogenesis and established his own research group (1998-2001). In October 2001 his research group moved to the Institute of Microbiology at the ETH Zurich.


The research in Wolf-Dietrich Hardt's group is focused on the molecular mechanisms of infectious diseases. This includes the evolution and adaptation of pathogens to new hosts and the molecular function of specific bacterial virulence factors. Currently, his lab has a strong focus on Salmonella Typhimurium pathogenesis and how these bacteria employ Type III secretion systems to manipulate signalling inside of host cells. This manipulation of the host by Salmonella Typhimurium is investigated using a wide spectrum of methods from biochemistry, molecular biology, immunology and cell biology.

Course Catalogue
551-0126-00L Fundamentals of Biology II: Cells
551-0314-00L Microbiology (Part II)
551-0509-00L Current Immunological Research in Zurich
551-1100-00L Infectious Agents: From Molecular Biology to Disease
551-1106-00L Progress Reports in Microbiology and Immunology
551-1109-00L Seminars in Microbiology
551-1110-00L Infection
551-1126-00L Technologies in Molecular Microbiology
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